Table 5.
Factors associated with medication adherence among epileptic patients (n = 292).
| Predictors | Medication adherence | COR (95% CI) | p value | AOR (95% CI) | p value | |
|---|---|---|---|---|---|---|
| Adherent, n (%) | Nonadherent, n (%) | |||||
| Age in years | ||||||
| 18-30 | 60 (59.4) | 112 (58.6) | 1 | 1 | 1 | 1 |
| 31-60 | 36 (35.6) | 76 (39.8) | 0.99 (0.60-1.64) | 0.971 | 1.83 (0.91-3.69) | 0.090 |
| >60 | 5 (5.0) | 3 (1.6) | 0.305 (0.07-1.32) | 0.113 | 0.62 (0.07-5.55) | 0.671 |
| Social drug use | ||||||
| No | 92 (91.1) | 157 (82.2) | 1 | 1 | 1 | 1 |
| Yes | 9 (8.9) | 34 (17.8) | 2.21 (1.02-4.82) | 0.045 | 0.79 (0.26-2.40) | 0.672 |
| Comorbidity | ||||||
| No | 85 (84.2) | 93 (48.7) | 1 | 1 | 1 | 1 |
| Yes | 16 (15.8) | 98 (51.3) | 5.60 (3.06-10.25) | <0.001 | 3.51 (1.20-10.31) | 0.022 |
| Types of seizure | ||||||
| GTC | 72 (71.3) | 143 (74.9) | 1 | 1 | 1 | 1 |
| Focal seizure | 14 (13.9) | 28 (14.7) | 1.85 (0.85-4.05) | 0.122 | 0.43 (0.16-1.16) | 0.096 |
| Absence seizure | 1 (1.0) | 5 (2.6) | 1.87 (0.71-4.93) | 0.208 | 0.72 (0.04-13.54) | 0.823 |
| Unclassified seizure | 14 (13.9) | 28 (14.7) | 4.67 (0.48-45.04) | 0.183 | 0.57 (0.21-1.55) | 0.272 |
| Number of medications | ||||||
| <3 | 62 (61.4) | 80 (41.9) | 1 | 1 | 1 | 1 |
| ≥3 | 39 (38.6) | 111 (58.1) | 2.21 (1.35-3.61) | 0.002 | 0.53 (0.21-1.36) | 0.185 |
| Seizure encounter | ||||||
| No | 88 (87.1) | 71 (37.2) | ||||
| Yes | 13 (12.9) | 120 (62.8) | 11.44 (5.96-21.96) | <0.001 | 5.45 (2.48-12.00) | <0.001 |
| Medication necessity belief | ||||||
| High necessity | 91 (90.1) | 138 (72.3) | 1 | 1 | 1 | 1 |
| Low necessity | 10 (9.9) | 53 (27.7) | 6.74 (2.80-16.26) | <0.001 | 3.38 (1.14-10.00) | 0.028 |
| Medication concern belief | ||||||
| Strong concern | 17 (16.8) | 112 (58.6) | 7.00 (3.86-12.71) | <0.001 | 4.23 (2.07-8.63) | <0.001 |
| Low concern | 84 (83.2) | 79 (41.4) | 1 | 1 | 1 | 1 |
| Over all medication belief | ||||||
| Negative belief | 11 (10.9) | 104 (54.5) | 9.78 (4.92-19.46) | <0.001 | 4.17 (1.74-10.02) | 0.001 |
| Positive belief | 90 (89.1) | 87 (45.5) | 1 | 1 | 1 | 1 |
COR: crude odds ratio; AOD: adjusted odds ratio; CI: confidence interval; GTC: generalized tonic seizure.