Table 1.
Haematological evaluation for acute toxicity.
| Control | 100mg/kg | 200mg/kg | 300mg/kg | 400mg/kg | 500mg/kg | |
|---|---|---|---|---|---|---|
| Hemoglobin (g/dL) | 16.52 ± 1.22 | 15.46 ± 1.12 | 15.62 ± 1.31 | 15.12 ± 2.21 | 16.13 ± 1.46 | 15.11 ± 2.08 |
| White blood cells (109/L) | 6.33 ± 0.32 | 6.11 ± 0.52 | 6.61 ± 0.58 | 5.99 ± 1.14 | 6.47 ± 053 | 5.71 ± 1.21 |
| Neutrophils (109/L) | 18.22 ± 0.23 | 18.41 ± 0.31 | 17.17 ± 2.35 | 17.22 ± 3.15 | 17.30 ± 0.50 | 18.33 ± 1.21 |
| Lymphocyte (109/L) | 78.21 ± 2.26 | 80.16 ± 5.31 | 76.86 ± 2.17 | 80.66 ± 3.11 | 79.23 ± 1.11 | 76.57 ± 1.55 |
| Monocytes (109/L) | 0.89 ± 0.11 | 1.00 ± 0.10 | 0.87 ± 0.12 | 0.87 ± 0.21 | 0.85 ± 0.12 | 0.88 ± 0.10 |
| Eosinophils (109/L) | 3.23 ± 3.68 | 3.13 ± 2.79 | 3.41 ± 3.21 | 3.22 ± 2.31 | 3.11 ± 2.45 | 3.51 ± 2.55 |
| Basophils (109/L) | 0.01 ± 0.21 | 0.01 ± 0.11 | 0.01 ± 0.02 | 0.01 ± 0.07 | 0.01 ± 0.10 | 0.01 ± 0.06 |
The results are expressed as the mean ±Standard error, (n=7). No significant difference could be detected between the different groups vs. the control group; Control, normal control group; 100 mg/kg, 100 mg/kg GTN- intraperitoneal treated group; 200 mg/kg, 200 mg/kg GTN- intraperitoneal treated group; 300 mg/kg, 300 mg/kg GTN- intraperitoneal treated group; 400 mg/kg, 400 mg/kg GTN- intraperitoneal treated group; 500 mg/kg, 500 mg/kg GTN- intraperitoneal treated group.