Table 3.
Ustekinumab cohort (n=20) | Anti-TNF cohort (n=40) | P value | |
---|---|---|---|
Indication of surgery: | |||
Medical refractory disease | ^5 (25%) | ^^3 (7.5%) | 0.19 |
Obstruction | 12 (60%) | 26 (65%) | |
Free bowel perforation | 2 (10%) | 2 (5%) | |
Intraabdominal abscess | 0 | 2 (5%) | |
Closure of ostomy | 0 | 3 (7.5%) | |
Others | *1 (5%) | **4 (10%) | |
Nature of surgery: | |||
Emergency | 11 (55%) | 10 (25%) | 0.04 |
Open laparotomy | 13 (65%) | 20 (50%) | 0.40 |
Type of surgery (n,%): Ileal resection |
6 (30%) | 9 (22.5%) | 0.54 |
Ileocolonic resection | 7 (35%) | 17 (42.5%) | 0.78 |
Subtotal colectomy | 4 (20%) | 3 (7.5%) | 0.21 |
Proctocolectomy | 2 (10%) | 0 | 0.10 |
Ostomy | 14 (70%) | 5 (12.5%) | <0.001 |
Primary anastomosis | 9 (45%) | 26 (65%) | 0.17 |
Stricturoplasty | 1 (5%) | 2 (5%) | 1.00 |
Fistula repair | 2 (10%) | 3 (7.5%) | 1.99 |
Hernia repair | 1 (5%) | 1 (2.5%) | 1.00 |
Cholecystectomy Appendectomy |
1 (5%) 0 |
4 (10%) 1 (2.5%) |
0.66 1.00 |
Adhesiolysis | 0 | 7 (17.5%) | 0.08 |
^inflammatory (ileo)colitis refractory to treatment x5
^^ inflammatory colitis refractory to treatment x 2, defunctioning loop ileostomy for refractory perianal disease x1
*cholecystectomy for cholecystitis
**cholecystectomy for porcelain gallbladder; cholecystectomy for gall bladder cancer; cholecystectomy for biliary colic x2