Table I.
Summary of immunohistochemistry results for diagnostic markers of ADC and SCLC.
| Samples | |||
|---|---|---|---|
| Markers | Histological Type | Primary lesion, surgical resection | EBUS + IBNA, biopsy |
| CKpan | Carcinoma | + | + |
| Ki-67 | Proliferation | 5% + | 90% |
| CK7 | ADC | + | Na |
| TTF-1 | ADC | Partially + | Partially + |
| Napsin A | ADC | + | Na |
| CK5/6 | SCC | − | Na |
| p40 | SCC | − | − |
| p63 | SCC | − | Na |
| CD56 | SCLC | − | Partially + |
| CgA | SCLC | − | − |
| Syn | SCLC | − | Partially + |
-, negative staining; +, positive staining; na, not tested; ADC, adenocarcinoma; SCC, squamous cell carcinoma; SCLC, small-cell lung cancer; EBUS + TBNA, endobronchial ultrasound-guided trans-bronchial needle aspiration; CKpan, pan-cytokeratin; CK, cytokeratin; TTF-1, thyroid transcription factor-1; CD56, neural cell adhesion molecule; CgA, chromogranin A; P, tumor protein; Syn, synaptophysin.