Table VI.
Multivariate analysis of independent variables associated with 21-gene recurrence score
| High/intermediate vs. low risk | |||
|---|---|---|---|
| Clinicopathological characteristic | OR | 95% CI | P-value |
| BMI | |||
| <24 | Ref | ||
| ≥24 | 3.590 | 1.296–9.947 | 0.014 |
| Histological grade | |||
| I–II | Ref | ||
| III | 3.478 | 1.139–10.627 | 0.029 |
| Molecular type | |||
| Luminal A | Ref | ||
| Luminal B | 0.839 | 0.294–2.393 | 0.743 |
| TYMS | 3.865 | 0.401–37.294 | 0.242 |
| TOP2A | 16.056 | 1.961–131.451 | 0.010 |
Bold indicates P<0.05. BMI, body mass index; CI, confidence interval; OR, odds ratio; Ref, Reference; TOP2A, DNA topoisomerase IIα; TYMS, thymidylate synthetase.