Table I.
Cox univariate and multivariate regression of genes involved.
| Univariate Cox regression | Multivariate Cox regression | |||||
|---|---|---|---|---|---|---|
| Gene | HR | 95% CI | P-value | HR | 95% CI | P-value |
| WDR54 | 2.30 | 1.30–4.10 | 0.004 | 0.68 | 0.32–1.47 | 0.330 |
| RPL26L1 | 3.90 | 1.40–10.00 | 0.007 | 4.95 | 1.38–17.73 | 0.014 |
| PSMC1 | 5.20 | 2.00–14.00 | 0.001 | 1.74 | 0.60–5.07 | 0.311 |
| SRPX | 1.50 | 1.10–2.10 | 0.006 | 0.99 | 0.68–1.44 | 0.945 |
| SMS | 2.80 | 1.40–5.50 | 0.003 | 1.49 | 0.60–3.66 | 0.387 |
| MTFMT | 4.50 | 1.50–13.00 | 0.007 | 1.26 | 0.32–4.91 | 0.736 |
| CNFN | 0.77 | 0.64–0.93 | 0.007 | 0.80 | 0.62–1.02 | 0.070 |
| CLEC10A | 0.59 | 0.44–0.80 | 0.001 | 0.79 | 0.49–1.25 | 0.314 |
| LRRC38 | 1.30 | 1.10–1.60 | 0.007 | 1.13 | 0.92–1.39 | 0.252 |
| RAB24 | 0.42 | 0.23–0.76 | 0.005 | 1.02 | 0.41–2.52 | 0.965 |
| PTPN9 | 4.10 | 1.40–12.00 | 0.008 | 1.52 | 0.36–6.38 | 0.570 |
| ZNF266 | 0.11 | 0.045–0.26 | <0.001 | 0.11 | 0.04–0.29 | <0.001 |
| CIITA | 0.60 | 0.43–0.83 | 0.002 | 0.98 | 0.59–1.62 | 0.924 |
| IL1RAP | 2.00 | 1.20–3.40 | 0.009 | 1.23 | 0.70–2.18 | 0.468 |
| ENSG00000261408 | 0.53 | 0.34–0.84 | 0.007 | 0.93 | 0.51–1.71 | 0.826 |
| ENSG00000261777 | 1.90 | 1.20–3.10 | 0.009 | 1.67 | 0.95–2.95 | 0.074 |
| ENSG00000265206 | 0.55 | 0.42–0.73 | <0.001 | 0.79 | 0.53–1.20 | 0.271 |
HR, hazard ratio; CI, confidence interval; WDR54, WD repeat domain 54; RPL26L1, ribosomal protein L26 like 1; PSMC1, proteasome 26S subunit, ATPase 1; SRPX, sushi repeat containing protein, X-linked; SMS, spermine synthase; MTFMT, mitochondrial methionyl-tRNA formyltransferase; CNFN, cornifelin; CLEC10A, C-type lectin domain containing 10A; LRRC38, leucine rich repeat containing 38; RAB24, member RAS oncogene family; PTPN9, protein tyrosine phosphatase, non-receptor type 9; ZNF266, zinc finger protein 266; CIITA, class II major histocompatibility complex transactivator; IL1RAP, interleukin 1 receptor accessory protein.