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. 2019 Mar 21;17(6):4835–4842. doi: 10.3892/ol.2019.10175

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Copyright: © Wen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of talin2 in MDA-MB-231 cells and breast cancer tissues. (A) Distribution of talin2 expression in tumor tissues and normal tissues based on IHC (magnification, ×400). (B) Semi-quantification of IHC results. ***P<0.001 compared with normal tissues. (C) Endogenous talin2 protein levels in talin2-depleted and control MDA-MB-231 cells, as measured by western blotting. (D) Relative mRNA expression levels of talin2 in talin2-depleted and control MDA-MB-231 cells, as measured by quantitative polymerase chain reaction. **P<0.01, ***P<0.001 compared with shRNA cntl. cntl, control; IHC, immunohistochemistry; shRNA, short hairpin RNA.