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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Pharmacotherapy. 2019 Jan 7;39(3):261–270. doi: 10.1002/phar.2201

Table 4.

Bacterial pathogens that developed new resistance distribution

New resistance
Cefepime
(n=61)
Meropenem
(n=103)
Piperacillin- tazobactam
(n=108)
Pathogens, n (%)
 Achromobacter species 6 (9.8) 2 (1.9) 1 (1)
 Acinetobacter baumannii 12 (19.7) 11 (10.7) 5 (4.9)
 Burkholderia cepacia 0 (0) 2 (1.9) 0 (0)
 Citrobacter species 3 (4.9) 0 (0) 8 (7.8)
 Enterobacter species 8 (13.1) 9 (8.7) 44 (42.7)
 Escherichia coli 14 (23.0) 2 (1.9) 10 (9.7)
 Klebsiella oxytoca 2 (3.3) 0 (0) 4 (3.9)
 Klebsiella pneumoniae 3 (4.9) 4 (3.9) 14 (13.6)
 Morganella morganii 0 (0) 0 (0) 0 (0)
 Proteus mirabilis 1 (1.6) 1 (1.0) 0 (0)
 Providencia species 0 (0) 1 (1.0) 0 (0)
 Pseudomonas aeruginosa 11 (18.0) 67 (65.0) 13 (12.6)
 Serratia species 0 (0) 0 (0) 8 (7.8)
 Stenotrophomonas maltophilia 1 (1.6) 3 (2.9) 0 (0)
Other rare gram-negative pathogen 0 (0) 0 (0) 1 (1.0)
Source of isolation, n (%)a
Blood 27 (23.1) 20 (11.4) 41 (16.9)
Respiratory specimen 50 (42.7) 88 (50.3) 90 (37.0)
Urine 27 (23.1) 34 (19.4) 41 (16.9)
Other 13 (11.1) 33 (18.9) 71 (29.2)
a

Different totals are due to some resistant pathogen being isolated from multiple culture sites in the same patient