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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Feb 14;197:212–219. doi: 10.1016/j.drugalcdep.2018.12.029

Table 2.

Associations of childhood adverse experiences and hypothesized mediators, by sex (N=9,569)

Odds of high level of mediator associated with every increase of 1 trauma versus no/low level of mediator
Males (N=4,295) Females (N=5,274)
% high level of mediator OR (95% CI) AOR (95% CI)* % high level of mediator OR (95% CI) AOR (95% CI)*
Internalizing factors
Depression (Wave I) 12.38 1.43 (1.28, 1.60) 1.38 (1.24, 1.55) 21.76 1.42 (1.31, 1.54) 1.38 (1.28, 1.49)
Depression (Wave III) 8.19 1.35 (1.20, 1.51) 1.32 (1.17, 1.49) 14.19 1.44 (1.33, 1.54) 1.37 (1.28, 1.47)
Depression (Wave IV) 11.45 1.34 (1.22, 1.47) 1.30 (1.17, 1.44) 16.93 1.43 (1.32, 1.54) 1.36 (1.25, 1.48)
Anxiety (Wave I) 26.15 1.27 (1.18, 1.37) 1.28 (1.19, 1.38) 37.65 1.38 (1.30, 1.47) 1.38 (1.30, 1.47)
Suicidality (Wave III) 6.34 1.27 (1.23, 1.42) 1.27 (1.13, 1.44) 7.06 1.48 (1.32, 1.67) 1.47 (1.30, 1.66)
Externalizing factors
Risk taking (Wave III) 19.75 1.09 (1.02, 1.78) 1.10 (1.02, 1.19) 14.23 1.10 (1.04, 1.16) 1.10 (1.04, 1.17)
Impulsivity (Wave III) 54.88 1.20 (1.11, 1.29) 1.21 (1.13, 1.31) 33.71 1.24 (1.17, 1.32) 1.22 (1.15, 1.30)
Delinquency (Wave I) 48.26 1.57 (1.45, 1.70) 1.57 (1.45, 1.70) 32.98 1.52 (1.42, 1.62) 1.49 (1.39, 1.59)
Delinquency (Wave III) 50.18 1.25 (1.15, 1.36) 1.26 (1.16, 1.36) 29.62 1.23 (1.15, 1.32) 1.20 (1.12, 1.29)

OR: odds ratio; AOR: adjusted odds ratio; CI: confidence interval

*

Adjusted for age, race/ethnicity, and poverty