Figure 1A-F–

Vascular findings in pulmonary hypertension associated with sarcoidosis: A) Atheroma (ATH) in large pulmonary artery, a finding in pulmonary hypertension of many causes; B) muscular intrapulmonary artery with medial hypertrophy and intimal hyperplasia also present in pulmonary hypertension of many causes; C) granulomatous arteritis with sarcoid granuloma (arrows) destroying the media of the artery (Art); D) pulmonary veno-occlusive disease, in this case with a granuloma in the wall of the vein (V) as well as generalized fibrosis thickening the vein wall; E and F) marked capillary proliferation in pulmonary capillary hemangiomatosis, a relatively rare finding in the lungs of patients with sarcoidosis and pulmonary hypertension (A trichrome/elastic stain x40, B and C trichrome elastic stain x200, D hematoxylin eosin stain x100, and F reticulin stain x100)