Table III.
Clinicopathological characteristics of 54 patients with clear cell renal cell carcinoma and their association with TUSC3 expression.
| TUSC3 expression | ||||
|---|---|---|---|---|
| Characteristics | n | Low, n (%) | High, n (%) | P-value |
| Age at surgery, years | 0.999 | |||
| <65 | 27 | 18 (66.6) | 9 (33.3) | |
| ≥65 | 27 | 17 (63.0) | 10 (37.0) | |
| Sex | 0.572 | |||
| Male | 34 | 21 (61.8) | 13 (38.2) | |
| Female | 20 | 14 (70.0) | 6 (30.0) | |
| Primary tumor size, cm | 0.030a | |||
| <7 | 38 | 21 (60.5) | 17 (39.5) | |
| ≥7 | 16 | 14 (87.5) | 2 (12.5) | |
| Tumor thrombus | 0.044a | |||
| None | 47 | 28 (59.6) | 19 (40.4) | |
| Level 0-IV | 7 | 7 (100.0) | 0 (0.0) | |
| Primary tumor classification | 0.039a | |||
| T1+T2 | 42 | 24 (57.1) | 18 (42.9) | |
| T3+T4 | 12 | 11 (91.7) | 1 (8.3) | |
| Regional lymph node involvement | 0.040a | |||
| N0 | 43 | 26 (60.5) | 17 (39.5) | |
| N1+N2 | 11 | 11 (100.0) | 0 (0.0) | |
| Distant metastasis | 0.044a | |||
| M0 | 47 | 28 (59.6) | 19 (40.4) | |
| M1 | 7 | 7 (100.0) | 0 (0.0) | |
| TNM stage | 0.039a | |||
| I+II | 42 | 24 (57.1) | 18 (42.9) | |
| III+IV | 12 | 11 (91.7) | 1 (8.3) | |
| Nuclear grade | 0.021a | |||
| 1+2 | 41 | 23 (56.1) | 18 (43.9) | |
| 3+4 | 13 | 12 (92.3) | 1 (7.7) | |
P-values were calculated using Fisher's exact test.
a
Considered statistically significant. TNM, Tumor-Node-Metastasis; TUSC3, tumor suppressor candidate 3.