Table IV.
Univariate and multivariate analyses of overall survival of patients with clear cell renal cell carcinoma.
| Overall survival | ||||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||
| Characteristics | HR (95% CI) | P-value | HR (95% CI) | P-value |
| Age at surgery (<65 years vs. ≥65 years) | 1.784 (1.077–3.531) | 0.062 | 1.580 (1.012–3.230) | 0.079 |
| Sex (male vs. female) | 0.728 (0.358–1.369) | 0.236 | 0.625 (0.310–1.158) | 0.291 |
| Primary tumor size (<7 cm vs. ≥7 cm) | 4.632 (2.653–6.758) | 0.016a | 5.220 (2.793–9.365) | 0.032a |
| Tumor thrombus (None vs. level 0-IV) | 9.458 (4.635–21.325) | 0.020a | 8.457 (3.656–17.632) | 0.018a |
| Primary tumor classification (T1+T2 vs. T3+T4) | 4.320 (2.542–9.326) | 0.022a | 4.550 (2.860–11.736) | 0.036a |
| Regional lymph node involvement (NX+N0 vs. N1+N2) | 7.236 (4.335–26.324) | 0.019a | 6.358 (3.886–23.656) | 0.039a |
| Distant metastasis (M0 vs. M1) | 8.873 (2.365–24.325) | 0.026a | 5.637 (1.875–17.639) | 0.044a |
| TNM stage (I+II vs. III+IV) | 3.369 (2.859–9.635) | 0.020a | 3.963 (3.582–12.362) | 0.037a |
| Nuclear grade (1+2 vs. 3+4) | 5.238 (3.596–11.387) | 0.015a | 4.698 (3.157–9.692) | 0.012a |
| TUSC3 expression (low vs. high) | 0.185 (0.102–3.112) | <0.001 | 0.326 (1.786–5.447) | 0.015a |
a
P<0.05. CI, confidence interval; HR, hazard ratio; TNM, Tumor-Node-Metastasis.