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. 2019 Apr 18;17(6):5403–5408. doi: 10.3892/ol.2019.10276

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — lncRNA-NEF overexpression inhibits migration of the human osteosarcoma cell lines MG-63 and U2OS, possibly through miRNA-21. lncRNA-NEF overexpression significantly inhibited, while miRNA-21 overexpression significantly promoted (A) migration and (B) invasion of cells of MG-63 and U2OS cell lines. miRNA-21 overexpression attenuated the inhibitory effects of lncRNA-NEF overexpression on the migration and invasion of cancer cells. *P<0.05. miRNA, micro RNA; lncRNA, long non-coding RNA; C, control; NEF, neighboring enhancer of FOXA2.