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. 2019 Apr 9;17(6):5343–5350. doi: 10.3892/ol.2019.10235

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — SIRT1 expression is upregulated in glioma tissues and cell lines. (A) The expression of SIRT1 was detected in human glioma tissues and adjacent non-tumor tissues using RT-qPCR. (B) The expression of SIRT1 in U87, U251, A172, T98 and HEB cell lines and normal brain tissue was detected using RT-qPCR. (C) The Kaplan-Meier survival curve of patients with glioma was created based on the expression levels of SIRT1 protein. **P<0.001 and ***P<0.001 compared with normal brain tissues. RT-qPCR, reverse transcription-quantitative polymerase chain reaction; SIRT1, sirtuin 1.