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. 2019 Mar 21;17(6):5139–5146. doi: 10.3892/ol.2019.10183

Table III.

Cox proportional hazards model.

A, Overall survival

Univariate analysis Multivariate analysis


Category HR 95% CI P-value HR 95% CI P-value
T 5.121 0.721–36.369 0.102
N 1.729 0.243–12.278 0.584
TNM stage 2.886 0.406–20.485 0.289
HG 7.198 0.652–79.503 0.107
TN 8.795 1.230–62.875 0.030 11.739   1.415–97.362 0.023
IL-6 10.785 1.122–103.693 0.039 13.230   1.285–136.214 0.030
CRP 2.970 0.41–21.100 0.277

B, Recurrence-free survival

Univariate analysis Multivariate analysis


Category HR 95% CI P-value HR 95% CI P-value

T 3.355 0.801–14.053 0.098 2.499 0.583–10.711 0.218
N 5.598 1.129–27.748 0.035 3.429 0.677–17.364 0.136
TNM stage 0.993 0.200–4.920 0.993
HG 3.172 0.708–14.206 0.131
TN 2.702 0.543–13.456 0.225
IL-6 3.637 0.733–18.040 0.114
CRP 23.865 2.930–194.408 0.003 18.571 2.240–153.949 0.007

HR, hazard ratio; CI, confidence interval; T, pathological T factor; N, pathological N factor; TNM, Tumor-Node-Metastasis; HG, histological grade; TN, triple-negative molecular subtype; IL-6, interleukin-6; CRP, C-reactive protein.