Table III.
A 31-gene signature for predicting radiosensitivity.
| Gene symbol | Uniprot accession no. | Description | Univariate Cox P-value | Coefficient | Hazard ratio | 95% CI |
|---|---|---|---|---|---|---|
| ACTN1 | P12814 | Alpha-actinin-1 | 0.746 | −0.054 | 0.947 | 0.68–1.31 |
| ANXA2 | P07355 | Annexin A2 | 0.102 | −0.299 | 0.741 | 0.52–1.06 |
| ANXA5 | P14668 | Annexin A5 | 0.588 | −0.097 | 0.907 | 0.64–1.29 |
| ARHGDIB | P52566 | Rho GDP-dissociation inhibitor 2 | 0.285 | 0.136 | 1.145 | 0.89–1.47 |
| CAPNS1 | P04632 | Calpain small subunit 1 | 0.629 | 0.138 | 1.148 | 0.66–2.01 |
| CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | 0.791 | 0.031 | 1.032 | 0.82–1.30 |
| CCND1 | P24385 | G1/S-specific cyclin-D1 | 0.900 | 0.012 | 1.012 | 0.84–1.22 |
| CD63 | P08962 | CD63 antigen | 0.687 | 0.075 | 1.077 | 0.75–1.55 |
| CORO1A | P31146 | Coronin-1A | 0.248 | 0.141 | 1.152 | 0.91–1.46 |
| CXCR4 | P61073 | C-X-C chemokine receptor type 4 | 0.756 | −0.029 | 0.971 | 0.81–1.17 |
| DAG1 | Q14118 | Dystroglycan | 0.197 | −0.200 | 0.818 | 0.60–1.11 |
| EMP2 | P54851 | Epithelial membrane protein 2 | 0.983 | 0.003 | 1.003 | 0.76–1.31 |
| HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | 0.088 | 0.187 | 1.206 | 0.97–1.49 |
| HTRA1 | Q92743 | Serine protease HTRA1 | 0.210 | 0.163 | 1.177 | 0.91–1.52 |
| ITGB5 | P18084 | Integrin beta-5 | 0.874 | −0.032 | 0.969 | 0.65–1.43 |
| LAPTM5 | Q13571 | Lysosomal-associated transmembrane 5 protein | 0.121 | 0.152 | 1.164 | 0.96–1.41 |
| LRMP | Q12912 | Lymphoid-restricted membrane protein | 0.553 | 0.086 | 1.089 | 0.82–1.45 |
| MYB | P10242 | Transcriptional activator Myb | 0.932 | −0.008 | 0.992 | 0.82–1.02 |
| PFN2 | P35080 | Profilin-2 | 0.518 | 0.056 | 1.058 | 0.89–1.25 |
| PIR | O00625 | Pirin | 0.043 | 0.237 | 1.268 | 1.01–1.59 |
| PKM2 | P14618 | Pyruvate kinase PKM | 0.985 | 0.003 | 1.003 | 0.70–1.43 |
| PTMS | P04550 | Parathymosin | 0.290 | 0.176 | 1.192 | 0.86–1.65 |
| PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | 0.350 | 0.096 | 1.100 | 0.90–1.34 |
| PTPRCAP | Q14761 | Protein tyrosine phosphatase receptor | 0.435 | 0.085 | 1.089 | 0.88–1.35 |
| PYGB | P11216 | Glycogen phosphorylase, brain form type C-associated protein | 0.622 | −0.063 | 0.939 | 0.73–1.21 |
| RAB13 | P51153 | Ras-related protein Rab-13 | 0.965 | 0.012 | 1.012 | 0.59–1.72 |
| RALB | P11234 | Ras-related protein Ral-B | 0.724 | −0.077 | 0.926 | 0.60–1.42 |
| SCRN1 | Q12765 | Secernin-1 | 0.683 | 0.060 | 1.062 | 0.80–1.42 |
| SQSTM1 | Q13501 | Sequestosome-1 | 0.218 | 0.197 | 1.218 | 0.89–1.67 |
| TWF1 | Q12792 | Twinfilin-1 | 0.277 | 0.282 | 1.325 | 0.79–2.20 |
| WAS | P42768 | Wiskott-Aldrich syndrome protein | 0.246 | 0.137 | 1.147 | 0.91–1.45 |
CI, confidence interval.