Table 3.
Comparison of Risks of ESRD and Death Between Patients With PA and Their EH Matches for the Whole PA Cohort and the APA Subgroup Only by Targeted Treatments
| Adrenalectomy | P | MRA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Therapeutic Option | Crude Hazard Ratio (95% CI) | P | Adjusted Hazard Ratio (95% CI) | P | Competing Hazard Ratio (95% CI) | Crude Hazard Ratio (95% CI) | P | Adjusted Hazard Ratio (95% CI) | P | Competing Hazard Ratio (95% CI) | P | |
| EH vs PA | ||||||||||||
| ESRD | 0.46 (0.23, 0.92) | 0.028 | 0.46 (0.23, 0.93) | 0.031 | 0.38 (0.19, 0.76) | 0.007 | 1.09 (0.85, 1.41) | 0.492 | 0.93 (0.72, 1.20) | 0.567 | 1.08 (0.83, 1.39) | 0.570 |
| Mortality | 0.22 (0.15, 0.34) | <0.001 | 0.22 (0.15, 0.34) | <0.001 | NA | NA | 1.05 (0.94, 1.18) | 0.381 | 1.05 (0.94, 1.18) | 0.380 | NA | NA |
| ESRD + mortality | 0.26 (0.18, 0.38) | <0.001 | 0.26 [0.18, 0.37) | <0.001 | NA | NA | 1.08 (0.97, 1.20) | 0.175 | 1.08 (0.97, 1.20) | 0.178 | NA | NA |
| EH vs APA | ||||||||||||
| ESRD | 0.53 (0.26, 1.11) | 0.092 | 0.43 (0.21, 0.89) | 0.024 | 0.55 (0.27,0.89] | 0.021 | 0.39 (0.12, 1.25) | 0.113 | 0.31 (0.10, 1.03) | 0.080 | 0.39 (0.12, 1.22) | 0.100 |
| Mortality | 0.30 (0.19, 0.46) | <0.001 | 0.31 (0.20, 0.47) | <0.001 | NA | NA | 0.67 (0.42, 1.07) | 0.095 | 0.61 (0.38, 0.99) | 0.045 | NA | NA |
| ESRD + mortality | 0.34 (0.23, 0.50) | <0.001 | 0.35 (0.24, 0.52) | <0.001 | NA | NA | 0.65 (0.42, 1.00) | 0.051 | 0.61 (0.39, 0.94) | 0.027 | NA | NA |
Abbreviation: NA, not available.