Table 3.
Clinical and pathological manifestations of IgAN patients grouped according to HECW1 levels.
| Variables | Low HECW1 Group (≤0.58, n = 20) | High HECW1 Group (>0.58, n = 20) | p value |
|---|---|---|---|
| Age (mean ± SD, year) | 35.8 ± 9.76 | 38.11 ± 11.65 | .88 |
| Gender (M/F, %) | 17 (60)/18 (40) | 27 (50)/20 (50) | .50 |
| SBP (mmHg, mean ± SD) | 126 ± 13 | 125 ± 11 | .67 |
| Proteinuria (g/24h, median, IQR) | 1.12 (0.45–3.80) | 1.25 (0.43–3.54) | .45 |
| eGFR (mL/min/1.73 m2, mean ± SD) | 83.88 ± 30.40 | 80.21 ± 22.78 | .83 |
| Uric acid (μmol/L, mean ± SD) | 411.23 ± 109.14 | 398.21 ± 80.44 | .54 |
| Plasma IgA1 (μg/mL, median, IQR) | 1728 (980–2558) | 1215 (765–1583) | .04 |
| Oxford classification (%) | |||
| M score (M0/M1) | 2 (10)/18 (90) | 4 (20)/16 (80) | .38 |
| E score (E0/E1) | 15 (75)/5 (25) | 13 (65)/7 (35) | .49 |
| S score (S0/S1) | 9 (45)/11 (55) | 13 (65)/7 (35) | .20 |
| T score (T0/T1/T2) | 10 (50)/8 (40)/2 (10) | 8 (40)/10 (50)/2 (10) | .80 |
| C score (C0/C1/C2) | 3 (15)/14 (70)/3 (15) | 7 (10)/8 (75)/5 (15) | .15 |
eGFR: estimated glomerular filtration rate; IQR: interquartile range; SBP: systolic blood pressure; SD: standard deviation.