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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Hypertension. 2019 Jun;73(6):1308–1318. doi: 10.1161/HYPERTENSIONAHA.118.12437

Figure 6. Additional β5i immunostaining patterns in context of HELLP syndrome.

Figure 6.

(A) Remarkable staining of extravillous trophoblasts (EVT) within a placental cell island (asterisk). (B) Placental disk EVTs (arrows) shown at higher magnification. (C) Placental cell island (asterisk) imaged after double immunofluorescence for β5i (red signal) and human leukocyte antigen (HLA)-G (EVT marker, green signal), plus DAPI (nuclear counterstain, blue signal). (D) Cellular co-localization of β5i and HLA-G in EVTs (arrow) shown at higher magnification. (E) Micrograph illustrating acellular formations floating in the intervillous space and stained positive for β5i (arrows). (F) Negative control (non-immune IgG) of the same placenta. Scale bar: 50 nm.