Figure 3.

Northern blot analyses of ADF/cofilin expression in adult mice. Cofilin-1 mRNA (top) is expressed at high levels in brain and liver; at moderate amounts in heart, spleen, lung, kidney, and testis; but is not expressed in skeletal muscle. The only isoform expressed in skeletal muscle is cofilin-2 (middle), which is also expressed at moderate levels in heart, liver, and testis, and at lower amounts in other organs. ADF (bottom) is expressed strongly in liver and at moderate levels in other organs, but is not found in skeletal muscle.