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. Author manuscript; available in PMC: 2020 Mar 27.
Published in final edited form as: J Am Chem Soc. 2019 Mar 13;141(12):5051–5061. doi: 10.1021/jacs.9b01693

Figure 2.

Figure 2.

Decoding A sites of the human mitochondrial, A1555G mutant mitochondrial and cytoplasmic ribosomes, and of the bacterial ribosome. The bacterial AGA binding pocket is boxed. The bacterial numbering scheme is illustrated for the AGA binding pocket. Changes from the bacterial ribosome binding pocket are coloured green. The A1555G mutant conferring hypersusceptibility to AGA ototoxicity is coloured red.