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Antibacterial Activity (μg.mL−1) for Wild-type and A1408G Mutant M. smegmatis.
| Wild-type | A1408G | Activity Lossa | |
|---|---|---|---|
| Paromomycin 1 | 0.12 | 16 | 133 |
| Propylamycin 5 | 0.16 | 16–32 | 100–200 |
| Gentamicin | 0.12 | >128 | >1067 |
| Tobramycin | 0.12 | >128 | >1067 |
| Amikacin | 0.06 | >128 | >2133 |
| Plazomicin | 0.03 | >128 | >4267 |
Activity Loss = MIC Mutant/MIC wild-type
