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. 2019 May 9;14(5):e0215023. doi: 10.1371/journal.pone.0215023

Table 2. Areas significantly responded to sound omission or correlated to other measures.

Region (BA) Talairach coordination (X, Y, Z) of peak location p-value
(FWE corrected, cluster level)
t-value (peak level) Number of significant voxels
Areas significantly responding to omission of sound in controls (Fig 4).
Lt. superior temporal gyrus (BA 41) (-59.4, -26.8, 8.7) 0.033 5.25 84
Areas with reduced BOLD activity in the left middle temporal gyrus in patients 8 (Fig 5).
Lt. middle temporal gyrus (BA 39) (-37,6–72.9, 18.4) 0.003 5.35 231
Areas where BOLD activity significantly correlated positively with MMN amplitude at the Fz site in patients (Fig 6).
Rt. superior temporal gyrus (BA 42) (57.4, -32.5, 10.8) 0.018 6.85 103
Areas where BOLD activity significantly correlated positively with PANSS scores of positive symptoms (Fig 7)
Rt. parahippocampal gyrus (BA 19) (41.6, -42.6, 2.1) 0.000 8.32 392
Areas where BOLD activity significantly correlated positively with PANSS scores of hostility and Positive symptoms according to Bell’s classification (Fig 8)
correlated with hostility
Rt. Insula (BA 13) (33.7, -41.8, 18.7) 0.003 6.87 146
correlated with positive symptoms
Rt. parahippocampal gyrus (BA19) (39.6, -40.7, 2.0) 0.000 9.19 486
Areas where BOLD activity significantly correlated positively with BOLD signal change in the bilateral Heschl’s Gyri. (Figs 10 and 11).
correlated Lt. Heschl gyrus
Lt. insula (BA 13) (43.6, -15.2, 6.3) 0.000 12.20 1107
Lt. postcentral gyrus (BA43) (63.4, -10.6, 20.8) 0.000 21.46 218
Lt. inferior parietal lobule (BA 40) (-55.4, -25.5, 34.4) 0.020 6.75 97
Rt insula (—4.0 -40.0, 14.9) 0032 5.57 88
correlated with Rt. Heschl gyrus
Rt. insula (BA 13) (43.6, 3.5, -6.9) 0.018 6.13 105
Lt. posterior cingulate(BA29) (-2.0, -42.0, 15.0) 0.008 7.96 123
Lt. middle frontal gyrus (BA 9) (-29.7, 30.3, 22.4) 0.005 5.60 134

BA: Brodmann area

FWE: family-wise error rate