Skip to main content
. Author manuscript; available in PMC: 2019 May 9.
Published in final edited form as: Biomater Sci. 2018 May 1;6(5):1189–1200. doi: 10.1039/c8bm00149a

Figure 4.

Figure 4

In vivo antitumor efficacy studies. (A) Schematic timeline of the experimental procedures. (B) MCF-7 tumor growth in athymic nude mice treated with Alb-NCs (40 mg Doxo/kg) and PEG-NCs (40 mg Doxo/kg). PBS was used as negative control. Three doses were administrated on Day 0 and Day 4 and Day 8. All of the data are represented as average ± SEM (n = 16). Unpaired T-Test (two tailed) with Welch’s correction was used for statistical analysis. The results were deemed significant at *p < 0.05, ** p < 0.01, *** p < 0.001. (C) Kaplan–Meier plots for all groups are shown. Loss of mice was because of treatment-related death, nontreatment-related death, or euthanasia after the end point (900 mm3) had been reached (n = 4).