Table 3. Analytical parameters.
| Robust | Prefrail | Frail | P value | |
|---|---|---|---|---|
| Hemoglobin, g/dL, mean (± SD) | 14.5 (1.4) | 14.1 (1.5) | 14.2 (1.4) | 0.12 |
| Hematocrit %, mean (± SD) | 44.0 (4.3) | 42.9 (4.3) | 43.2 (4.5) | 0.14 |
| Platelets (x103/uL), mean (± SD) | 213.3 (56.3) | 214.6 (63.4) | 212.2 (59.2) | 0.95 |
| Glucose mg/dL, mean (± SD) | 93.9 (16.2) | 94.4 (19.2) | 102.0 (17.4) | 0.10 |
| Creatinine mg/dL, mean (± SD) | 0.9 (0.1) | 0.8 (0.2) | 1.3 (1.1) | 0.03 |
| Estimated glomerular filtration rate (ml/min/1.73 m2) (n, %) | 92.6 (16.5) | 92.2 (18.7) | 66.9 (26.5) | 0.004 a,b |
| HDL-c, mg/dL mean (± SD) | 50.6 (14.4) | 52.0 (16.4) | 52.6 (18.7) | 0.64 |
| LDL-c, mg/dL, mean (± SD) | 101.5 (27.0) | 106.9 (32.4) | 114.9 (35.0) | 0.43 |
| Total cholesterol, mg/dL, (mean (± SD) | 178.9 (33.1) | 184.3 (36.8) | 194.9 (38.3) | 0.54 |
| Triglycerides, mg/dL, mean (± SD) | 146.2 (122.2) | 136.8 (79.2) | 150.1 (105.5) | 0.96 |
| AST, IU/L, mean (± SD) | 23.2 (9.9) | 22.3 (12.3) | 19.5 (7.4) | 0.09 |
| ALT, IU/L, mean (± SD) | 25.3 (13.9) | 23.3 (17.6) | 18.6 (8.2) | 0.02 |
| Total bilirubin, mean (± SD) | 0.7 (0.9) | 0.6 (0.5) | 0.3 (0.1) | 0.07 |
| Albumin, g/dL, mean (± SD) | 4.5 (0.3) | 4.5 (0.2) | 4.2 (0.8) | 0.001 a,b |
| Total proteins, g/dL, mean (± SD) | 7.2 (0.4) | 7.2 (0.4) | 6.8 (0.4) | 0.06 |
| C-reactive protein g/dL, mean (± SD) | 2.0 (2.4) | 5.3 (18.0) | 21.8 (53.5) | 0.01 c |
| Fibrinogen, mg/dL, mean (± SD) | 356.4 (62.7) | 371.5 (84.5) | 410.7 (114.0) | 0.13 |
Note: ALT: Alanine amino transferase; AP: Alkaline phosphatase; AST: Aspartate amino transferase; HDL-c: High-density lipoprotein cholesterol; FIB-4: Fibrosis-4 index; GGT: Gamma-glutamyl transferase; LDL: Low-density lipoprotein cholesterol; SD = Standard deviation; TC: Total cholesterol; TGD: Triglycerides. P-value is significant at the 0.05 level (a robust vs frail; b prefrail vs frail; c robust vs prefrail).