Table 1.

Type of interactions in embedded pragmatic clinical trials

Intervention Level	Types of Interactions	Number of Studies
Population1	Prompts and reminders (eg, for screening) to population	5
Patient	Comparing effectiveness of treatments	9
Clinician	Prompts and reminders to patients	22
	Financial	4
	Multifaceted (often directed both to patients and clinicians)	9
	Education and information (may be to patients or clinicians)	10
Organization	Decision support tools	18
	Prompts and reminders to clinician	9
	Audit and feedback	16
	Organizational changes (eg, task shifting)	7
	Care management	4

Note: Individuals for whom a health system is responsible or residents of a geographic region.