Table 5.
Mean comparisons based on alcohol dependence, cocaine dependence, and depression with neurocognitive (NC) functioning (N = 38).
Neurocognitive domain | Diagnosis of alcohol dependence |
Diagnosis of cocaine dependence |
Lifetime diagnosis of depression |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Dependent (n = 13) |
Non-dependent (n = 25) |
Dependent (n = 17) |
Non-dependent (n = 21) |
Depressed (n = 13) |
Non-depressed (n = 25) |
|||||||
M (SD) | M (SD) | t-Test | Cohen's d |
M (SD) | M (SD) | t-Test | Cohen's d |
M (SD) | M (SD) | t-Test | Cohen's d |
|
Global NC functioning | 37.9 (6.5) | 42.9 (5.8) | 2.4* | 0.68 | 39.6 (6.8) | 42.5 (6.0) | 1.4 | 0.46 | 39.8 (8.8) | 41.9 (4.9) | 0.82 | 0.32 |
Learning | 33.1 (12.2) | 34.4 (9.2) | 0.4 | 0.06 | 34.6 (10.8) | 33.4 (9.8) | −0.4 | 0.05 | 33.9 (13.5) | 34.0 (8.3) | 0.03 | 0.00 |
Memory | 32.3 (12.0) | 36.1 (10.6) | 1.0 | 0.17 | 34.3 (11.8) | 35.2 (10.8) | 0.3 | 0.04 | 34.4 (13.7) | 35.0 (9.8) | 0.16 | 0.03 |
Executive functioning | 37.2 (5.9) | 44.5 (6.7) | 2.9* | 1.13 | 38.6 (6.7) | 43.6 (6.6) | 2.3* | 0.75 | 40.6 (7.4) | 41.8 (6.9) | 0.44 | 0.17 |
Motor | 34.2 (9.0) | 43.8 (7.6) | 3.4* | 1.19 | 36.4 (9.6) | 43.5 (8.0) | 2.4* | 0.81 | 36.3 (8.6) | 42.6 (9.2) | 1.9 | 0.70 |
Attention/working Memory | 40.4 (7.3) | 44.0 (8.3) | 1.3 | 0.45 | 40.8 (8.3) | 44.3 (7.7) | 1.3 | 0.44 | 43.0 (8.8) | 42.9 (7.8) | 0.12 | 0.01 |
Verbal fluency | 44.5 (8.7) | 45.0 (9.9) | 0.18** | 0.05 | 45.3 (8.7) | 45.3 (10.2) | 0.3 | 0.00 | 43.7 (12.8) | 45.4 (7.6) | 0.53 | 0.18 |
Processing speed | 43.2 (5.8) | 50.7 (8.5) | 2.8* | 0.97 | 45.7 (9.3) | 50.1 (7.3) | 1.6 | 0.53 | 46.8 (11.6) | 48.8 (6.4) | 0.72 | 0.24 |
Note. Mean and Standard Deviations (M, SD) based on average T Scores; T-Scores < 40 = NC impairment; Diagnosis assessed using the Composite Diagnostic Interview (CIDI).
p < 0.05.
p < 0.001.