Fig. 5.

Binding of VWF/ULVWF (ULVWF) to C3 protein is blocked by anti-A3 domain antibody. Biosensors coated with C3 were dipped onto wells containing a solution of ULVWF mixed with mouse IgG (25 μg/mL) or anti-VWF A3 domain antibody, MR-5 (25 μg/mL). The MR-5 antibody inhibited ∼70% of the ULVWF–C3 binding. The graph shows two separated experiments.