Table 2.
Longitudinal dual x-ray absorptiometry body composition measures of 32 women with breast cancer participating in a presurgical weight loss triala having low versus high Akkermansia muciniphila relative abundance at baseline.
| Low A. muciniphila (n=16) | High A. muciniphila (n=16) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Follow-up | Baseline | Follow-up | ||||||||
| Mean | SD | Mean | SD | pb | Mean | SD | Mean | SD | pb | pc | |
| Weight (kg) | 96.98 | 13.57 | 94.71 | 13.20 | 0.0003 d | 85.40 | 17.59 | 83.34 | 17.62 | 0.001 d | 0.766 |
| Lean body mass (kg) | 47.23 | 5.55 | 46.56 | 5.32 | 0.026 | 43.63 | 6.72 | 42.99 | 6.83 | 0.046 | 0.420 |
| Fat mass (kg) | 46.44 | 9.00 | 44.87 | 8.70 | 0.003 d | 38.91 | 11.17 | 37.02 | 11.42 | 0.003 d | 0.849 |
| Fat percentage | 49.3% | 3.6% | 48.8% | 3.5% | 0.097 | 46.5% | 4.4% | 45.5% | 4.6% | 0.005 d | 0.499 |
a
Mean time from baseline to follow-up was 30±9 days.
b
Within group differences from baseline to follow-up
c
Differences between groups from baseline to follow-up
d
Significant difference from baseline to follow-up within group: p<0.05/4 = 0.0125