Table 2. HLA-G 14–bp Ins/Del polymorphism genotype distribution and allele frequency in cases and controls.
First author | Year | Genotype (n) | Allele frequency (n) | HWE | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | |||||||||||
Total | Del/Del | Ins/Del | Ins/Ins | Total | Del/Del | Ins/Del | Ins/Ins | Del | Ins | Del | Ins | |||
Gao et al. [21] | 2011 | 132 | 54 | 66 | 12 | 254 | 77 | 128 | 46 | 174 | 90 | 282 | 220 | 0.852 |
Xu et al. [35] | 2017 | 113 | 52 | 44 | 17 | 150 | 51 | 75 | 24 | 148 | 78 | 177 | 123 | 0.919 |
Zidi et al. [36] | 2016 | 104 | 31 | 52 | 20 | 83 | 20 | 42 | 20 | 114 | 92 | 82 | 82 | 0.975 |
Zambra et al. [37] | 2016 | 187 | 85 | 83 | 19 | 129 | 45 | 58 | 26 | 253 | 121 | 148 | 110 | 0.656 |
Yang et al. [22] | 2014 | 315 | 169 | 110 | 36 | 400 | 188 | 176 | 36 | 448 | 182 | 552 | 248 | 0.850 |
Silva et al. [38] | 2013 | 55 | 11 | 29 | 15 | 50 | 19 | 19 | 12 | 51 | 59 | 57 | 43 | 0.283 |
Agnihotri et al. [39] | 2017 | 383 | 82 | 212 | 89 | 383 | 122 | 175 | 86 | 376 | 390 | 419 | 347 | 0.876 |
Wisniewski et al. [40] | 2015 | 319 | 111 | 160 | 48 | 465 | 157 | 231 | 77 | 382 | 256 | 545 | 385 | 0.311 |
Teixeira et al. [41] | 2013 | 109 | 49 | 44 | 16 | 202 | 70 | 87 | 45 | 142 | 76 | 227 | 177 | 0.205 |
Haghi et al. [42] | 2015 | 227 | 56 | 127 | 44 | 255 | 52 | 154 | 49 | 239 | 215 | 258 | 252 | 0.004 |
Garziera et al. [43] | 2016 | 308 | 97 | 138 | 73 | 294 | 114 | 122 | 58 | 332 | 284 | 350 | 238 | 0.059 |
Chen et al. [44] | 2012 | 239 | 86 | 123 | 30 | 467 | 155 | 237 | 70 | 295 | 183 | 547 | 377 | 0.412 |
Tawfeek et al. [45] | 2018 | 150 | 40 | 102 | 8 | 100 | 18 | 44 | 38 | 182 | 118 | 80 | 120 | 0.707 |
Dardano et al. [23] | 2012 | 183 | 47 | 96 | 40 | 245 | 84 | 110 | 51 | 190 | 176 | 278 | 212 | 0.409 |
Ramos et al. [11] | 2014 | 80 | 18 | 54 | 8 | 191 | 57 | 98 | 36 | 90 | 70 | 212 | 170 | 0.867 |
Eskandari-Nasab et al. [46] | 2013 | 236 | 80 | 106 | 50 | 203 | 49 | 91 | 63 | 266 | 206 | 189 | 217 | 0.368 |
Lau et al. [24] | 2011 | 153 | 66 | 58 | 29 | 404 | 146 | 194 | 64 | 190 | 116 | 486 | 322 | 0.973 |
Kim et al. [47] | 2013 | 270 | 159 | 93 | 18 | 91 | 61 | 28 | 2 | 411 | 129 | 150 | 32 | 0.841 |
Jiang et al. [13] | 2011 | 318 | 187 | 113 | 18 | 599 | 304 | 241 | 54 | 487 | 149 | 849 | 349 | 0.822 |
Jeong et al. [48] | 2014 | 80 | 54 | 21 | 5 | 80 | 44 | 32 | 4 | 129 | 31 | 120 | 40 | 0.837 |
Ferguson et al. [49] | 2012 | 539 | 184 | 242 | 113 | 833 | 272 | 399 | 162 | 610 | 468 | 943 | 723 | 0.770 |
Bortolotti et al. [50] | 2014 | 100 | 49 | 40 | 11 | 100 | 38 | 40 | 22 | 138 | 62 | 116 | 84 | 0.201 |
Castelli et al. [20] | 2008 | 80 | 28 | 37 | 15 | 107 | 35 | 50 | 22 | 93 | 67 | 120 | 94 | 0.868 |
Bielska et al. [51] | 2015 | 207 | 49 | 91 | 67 | 150 | 33 | 89 | 28 | 189 | 225 | 155 | 145 | 0.071 |
de Figueiredo-Feitosa et al. [52] | 2017 | 94 | 34 | 47 | 13 | 156 | 61 | 65 | 30 | 115 | 73 | 187 | 125 | 0.255 |