Table 2.
Dysregulated miRs in Profile BM and A.
| Profile BM: SSc-BM-MSCs vs HC-BM-MSCs | RQ: relative quantification | p |
|---|---|---|
| miRs (miRbase ID) | ||
| hsa-miR-200b-3p | 0,126 | 0,015 |
| hsa-miR-642a-5p | 0,198 | 0,048 |
| hsa-miR-483-3p | 0,242 | 0,045 |
| hsa-miR-519b-3p | 0,307 | 0,024 |
| hsa-miR-875-5p | 0,377 | 0,032 |
| hsa-miR-489-3p | 0,456 | 0,028 |
| hsa-miR-432-3p | 0,584 | 0,041 |
| hsa-miR-30d-3p | 0,673 | 0,035 |
| hsa-miR-335-3p | 0,767 | 0,003 |
| hsa-miR-30e-3p | 1,324 | 0,016 |
| hsa-miR-454-3p | 1,550 | 0,038 |
| hsa-miR-10b-3p | 2,351 | 0,044 |
| hsa-miR-629-3p | 2,361 | 0,008 |
| hsa-miR-432-5p | 2,500 | 0,028 |
| hsa-miR-668-3p | 15,389 | 0,048 |
| Profile A: SSc-A-MSCs vs HC-A-MSCs | RQ: relative quantification | p |
| miRs (miRbase ID) | ||
| hsa-miR-218-5p | 0,226 | 0,037 |
| hsa-miR-135b-5p | 0,250 | 0,008 |
| hsa-miR-199b-5p | 0,328 | 0,013 |
| hsa-miR-204-5p | 0,329 | 0,03 |
| dme-mir-7 | 0,393 | 0,038 |
| hsa-miR-500a-5p | 0,406 | 0,044 |
| hsa-miR-423-5p | 0,436 | 0,032 |
| hsa-miR-146a-5p | 0,439 | 0,046 |
| hsa-miR-708-5p | 0,458 | 0,042 |
| hsa-miR-155-5p | 0,459 | 0,034 |
| hsa-miR-146b-5p | 0,480 | 0,047 |
| hsa-miR-185-5p | 0,518 | 0,029 |
| hsa-miR-10a-5p | 0,557 | 0,029 |
| hsa-miR-222-5p | 0,620 | 0,02 |
| hsa-miR-766-3p | 0,640 | 0,03 |
| hsa-miR-1274A | 1,391 | 0,019 |
| hsa-miR-1271-5p | 1,480 | 0,044 |
| hsa-miR-27a-5p | 1,621 | 0,037 |
| hsa-miR-573 | 1,703 | 0,049 |
| hsa-miR-1227-3p | 2,445 | 0,016 |
| hsa-miR-1225-3p | 2,608 | 0,014 |
| hsa-miR-1267 | 2,742 | 0,024 |
List of significantly dysregulated miRs in Profile BM and A. Significant miRs expression changes were identified using a threshold of p < 0,05 (p value calculation based on 2−dCt).