Table 3.

Correlation of total and regional brain volumes with EDSS and SDMT in all the study patients at the study baseline and at 2 years.

		Baseline		Follow-up
Variable	Covariate	Pearson coorelation	p-value	Pearson coorelation	p-value
EDSS	Total BP vol.	-0.387	0.009	−0.354	0.016
	Total WM vol.	-0.279	0.045	−0.220	0.097
	Total GM vol.	-0.423	0.005	−0.395	0.009
	WM lesion vol.	0.271	0.045	0.363	0.015
	Putamen vol.	-0.295	0.034	−0.295	0.035
	Hippocampus vol.	-0.317	0.025	−0.301	0.034
	Thalamus vol.	-0.335	0.018	−0.433	0.005
	Nucleus caudatus vol.	-0.343	0.016	−0.266	0.052
	Globus pallidus vol.	-0.245	0.062	−0.250	0.062
	Cerebellum WM vol.	-0.452	0.003	−0.549	<0.001
SDMT	Total BP vol.	0.364	0.009	0.384	0.006
	Total WM vol.	0.278	0.043	0.281	0.043
	Total GM vol.	0.387	0.006	0.401	0.006
	WM lesion vol.	-0.545	<0.001	−0.536	<0.001
	Putamen vol.	0.282	0.041	0.255	0.065
	Hippocampus vol.	0.382	0.006	0.332	0.018
	Thalamus vol.	0.418	0.004	0.419	0.004
	Nucleus caudatus vol.	0.339	0.014	0.250	0.067
	Globus pallidus vol	0.201	0.131	0.177	0.188
	Cerebellum WM vol.	0.478	<0.001	0.524	<0.001

The bold values indicate statistically significant p-values.