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. 2019 May 3;10:984. doi: 10.3389/fimmu.2019.00984

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Copyright © 2019 Huang, Zhao, Liu, Xu, Su, Qin and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Stable gene silencing reduces the motility behavior on soft agar plates of P. plecoglossicida. Diameter of the colony of each strain was presented as mean ± SD, n = 6. Means of treatments not sharing a common letter are significantly different at P < 0.05. (B) Biofilm formation of wild-type and stable silenced strains. Data are presented as mean ± S.D. (n = 6). Means of treatments not sharing a common letter are significantly different at P < 0.05. (C) The dynamic distribution of Wild type and RNAi strains in host spleen. Data are shown as means ± SD from three independent biological replicates. **P < 0.01.