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. 2019 May 3;10:928. doi: 10.3389/fmicb.2019.00928

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Copyright © 2019 Chen, Al-Shayeb, Méheust, Li, Doudna and Banfield.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prophage and restriction modification systems are detected in the genomes of Roizmanbacteria C2-Gp3. (A) Scaffold 44 includes prophage, a restriction-modification system and an apparently degenerate Type III-A CRISPR-Cas system. (B) The proteins in the restriction-modification system shown in (A). (C) Prophage genes targeted by spacers are shown in black and the number of spacers targeting each open reading frame (ORF) is listed in brackets following the annotation. Genes not targeted by CRISPR spacers are shown in orange (top panel). The genome affiliations of spacers targeting the prophage are indicated in the bottom panel.