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Membrane curvature generation by proteins. Onset of membrane tubulation induced by 48 copies of α-Syn100 (yellow) interacting with a membrane composed of 85296 POPG lipids (blue tails, red headgroups). Water is not shown for clarity. Snapshot is obtained at 300 ns simulation time with the Martini model. The budding tubule extends ∼25 nm above the bulk lipid bilayer. Adapted from ref (533). Copyright 2014 American Chemical Society.
