Table 2.
End‐Diastolic NRC at Rest and Peak Exercise
| HFpEF (n=30 | HT (n=17) | Healthy (n=17) | P Value (Overall) | P Values for 2‐Way Comparisons if Overall Significant | |||
|---|---|---|---|---|---|---|---|
| HFpEF vs HT | HFpEF vs Healthy | HT vs Healthy | |||||
| NRC (dias) rest | 1.09 (0.01) | 1.10 (0.02) | 1.09 (0.02) | 0.80 | |||
| NRC (dias) peak exercise | 1.54 (0.07) | 1.27 (0.06) | 1.14 (0.03) | 0.0001 | 0.006a | 0.0001a | 0.241 |
| ΔNRC (dias)b | 0.45 (0.06) | 0.17 (0.05) | 0.06 (0.03) | 0.0001 | 0.0014a | 0.0001a | 0.472 |
Values are mean (SEM). HFpEF indicates heart failure with preserved ejection fraction; HT, hypertensive controls; NRC, normalized radius of curvature; ΔNRC, change in normalized radius of curvature.
a
P (adjusted)≤0.017.
b
The change in end‐diastolic NRC on exercise was significant for HFpEF patients (P<0.001), but not hypertensive (P=0.38) or normotensive controls (P=0.93).