Table 3.

Echocardiographic Correlates With Biomarkers in Obese Participants

Biomarker	Variable	ρ	P Value
GAL3	Diastolic function
	Mean e′	−0.30	<0.001
	Mitral E/A ratio	−0.27	0.002
	E/e′	0.30	<0.001
	LAV indexed to BSA	−0.04	0.68
	LV remodeling
	LVM indexed to height2.7	−0.05	0.56
	LVM/LVEDV ratio, g/mL	0.07	0.47
	Right heart structure/function
	TAPSE	0.01	0.91
	PASP	0.33	<0.001
	TAPSE/PASP ratio	−0.30	0.002
FSTL3	Diastolic function
	Mean e′	−0.35	<0.001
	Mitral E/A ratio	−0.34	<0.001
	E/e′	0.31	<0.001
	LAV indexed to BSA	−0.21	0.02
	LV remodeling
	LVM indexed to height2.7	0.04	0.67
	LVM/LVEDV ratio, g/mL	0.12	0.19
	Right heart structure/function
	TAPSE	−0.03	0.80
	PASP	0.21	0.02
	TAPSE/PASP ratio	−0.24	0.02
NT‐proBNP	Diastolic function
	Mean e′	−0.08	0.40
	Mitral E/A ratio	−0.20	0.03
	E/e′	0.08	0.42
	LAV indexed to BSA	−0.05	0.59
	LV remodeling
	LVM indexed to height2.7	0.05	0.59
	LVM/LVEDV ratio, g/mL	−0.03	0.78
	Right heart structure/function
	TAPSE	0.04	0.67
	PASP	0.11	0.25
	TAPSE/PASP ratio	−0.18	0.08

BSA indicates body surface area; FSTL3 indicates follistatin‐like 3 peptide; GAL3, galectin–3; LAV, left atrial volume; LV, left ventricular; LVEDV, left ventricular end‐diastolic volume; LVM, left ventricular mass; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; PASP, pulmonary artery systolic pressure; TAPSE, tricuspid annular plane systolic excursion.