Table 5.
Plasma apo(a) and the Kinetics of apo(a) and LDL‐apoB‐100 at Baseline in the 63 Subjects Grouped According to apo(a) Isoform Size
Characteristics | Apo(a) Isoform Size | |
---|---|---|
Small (KIV Repeats ≤22) | Large (KIV Repeats >22) | |
Predominant apo(a) isoform KIV | 18 (17–19)a | 28 (27–29) |
Apo(a), nmol/L | 33 (24–44)a | 13 (11–16) |
Apo(a) FCR, pool/day | 0.32 (0.29–0.37)b | 0.53 (0.46–0.61) |
Apo(a) PR, nmol/kg per day | 0.47 (0.34–0.66)c | 0.31 (0.26–0.38) |
LDL‐apoB‐100, mg/L | 455±150 | 461±137 |
LDL‐apoB‐100 FCR, pools/day | 0.43±0.13 | 0.49±0.13 |
LDL‐apoB‐100 PR, mg/kg per day | 8.9±4.3 | 9.9±3.2 |
Values expressed as mean±SD or geometric mean (95% CI). Apo indicates apolipoprotein; FCR, fractional catabolic rate; KIV, kringle‐IV; LDL, low‐density lipoprotein; PR, production rate.
P<0.001.
P<0.01.
P<0.05.