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. 2019 Mar 22;8(7):e011058. doi: 10.1161/JAHA.118.011058

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Myocardial blood flow (MBF) calculated using sorted k ₁₁ (MBF _k11/MBF _k11 ^DP), k ₂₂ (MBF _k22/MBF _k22 ^DP), or k ₃₃ (MBF _k33/MBF _k33 ^DP). A, MBF considering constant arteriole–venule (AV) drop in pressure (DP) of 19.5 mm Hg and a path length of 512 μm independent of the tissue condition. B, MBF considering varying AV DP according to the tissue condition and a path length of 512 μm. The DPs for these simulations are the mean values presented in Table 1. In both cases, calculations have been performed considering constant hematocrit of 0.4 in all vessel segments. *P<0.05. MI indicates myocardial infarction.