Table 1.
Changes in Permeability Tensors myocardial blood flow and arteriole‐venule drop in pressure in the Infarcted and Remote Zones of the Heart After MI
| Calculated metrics | I1MI | I3MI | I7MI | I45MI | R1MI | R3MI | R7MI | R45MI | Basal |
|---|---|---|---|---|---|---|---|---|---|
| k 11, mm3/s/kg | 0.0052±0.003 | 0.0033±0.0024 | 0.0043±0.0019 | 0.0098±0.0068 | 0.003±0.0025 | 0.0022±0.001 | 0.0032±0.0022 | 0.0061±0.0023 | 0.0035±0.0032 |
| k 22, mm3/s/kg | 0.0026±0.0013 | 0.0013±0.0021 | 0.0019±0.0014 | 0.0039±0.0033 | 0.0011±0.0007 | 0.0009±0.0004 | 0.0016±0.0014 | 0.0024±0.0013 | 0.001±0.0008 |
| k 33, mm3/s/kg | 0.0013±0.0012 | 0.0006±0.0011 | 0.0007±0.0008 | 0.0014±0.0016 | 0.0005±0.0004 | 0.0004±0.0003 | 0.0007±0.0008 | 0.0013±0.0008 | 0.0006±0.0005 |
| MBF k 11, mL/min/100 g | 295.72±167.16 | 186.66±133.4 | 242.59±107.91 | 550.63±383.62 | 169.19±139.06 | 121.7±56.24 | 182.31±124.75 | 341.27±130.64 | 197.66±179.11 |
| MBF k 22, (mL/min/100 g) | 149.3±74.15 | 71.42±117.29 | 106.86±78.7 | 219.27±188.57 | 63.78±39.05 | 48.16±21.97 | 87.65±77.65 | 133.04±74.75 | 57.07±45.98 |
| MBF k 33, (mL/min/100 g) | 73.06±66.09 | 31.17±59.56 | 39.4±45.2 | 78.38±91.84 | 27.28±20.63 | 19.81±15.6 | 38.69±43.52 | 72.4±47.7 | 34.54±28.93 |
| DP, mm Hg | 7.16±4.13 | 16.94±10.81 | 5.1±2.83 | 2.85±1.84 | 23.18±12.86 | 21.31±13.36 | 20.41±11.78 | 9.88±4.27 | 26.31±25.9 |
| MBFk11 DP, mL/min/100 g | 77.12±47.4 | 88.21±60.1 | 31.79±13.26 | 30.95±16.51 | 111.01±138.75 | 62.74±38.07 | 121.54±99.22 | 114.14±52.03 | 215.2±205.92 |
| MBFk22 DP, mL/min/100 g | 39.38±22.66 | 31±42.28 | 13.98±9.12 | 13.95±11.88 | 40.81±29.82 | 25.21±14.52 | 60.02±60.2 | 45.33±30.11 | 59.5±56.24 |
| MBFk33 DP, mL/min/100 g | 18.55±18.05 | 11.96±17.28 | 5.6±5.74 | 4.97±5.41 | 17.96±17.36 | 11.31±9.66 | 27.28±34.25 | 24.17±16.7 | 36.1±33.38 |
Data are shown as mean±SD of diagonal elements of permeability tensors (k 11, k 22, and k 33); MBF according to k 11, k 22, and k 33 and constant AV DP (MBFk11, MBFk22, and MBFk33); AV DP; and MBF using the calculated varying DP shown in row 7 (MBFk11 DP, MBF k22 DP, and MBF k33 DP). The AV path is assumed equal to 512 μm. I1MI, I3MI, I7MI, and I45MI indicate infarcted areas at 1, 3, 7, and 45 days, respectively, after MI. Similarly, R1MI, R3MI, R7MI, and R45MI indicate remote areas at 1, 3, 7, and 45 days, respectively, after MI. AV indicates arteriole–venule; DP, drop in pressure. MBF, myocardial blood flow; MI, myocardial infarction.