Table 2.
Blood Flow Properties Calculated Without the Application of the Scaling Factor for Simplification of the Network After Deletion of Blind Ends
| Calculated metrics | I1MI | I3MI | I7MI | I45MI | R1MI | R3MI | R7MI | R45MI | Basal |
|---|---|---|---|---|---|---|---|---|---|
| k 11, mm3/s/kg | 0.0037±0.0023 | 0.0018±0.0012 | 0.0022±0.0009 | 0.0038±0.002 | 0.0017±0.0021 | 0.001±0.0006 | 0.0021±0.0017 | 0.004±0.0018 | 0.0028±0.0027 |
| k 22, mm3/s/kg | 0.0019±0.0011 | 0.0006±0.0009 | 0.0009±0.0006 | 0.0017±0.0014 | 0.0006±0.0004 | 0.0004±0.0002 | 0.001±0.001 | 0.0016±0.0011 | 0.0008±0.0007 |
| k 33, mm3/s/kg | 0.0009±0.0009 | 0.0002±0.0004 | 0.0004±0.0004 | 0.0006±0.0007 | 0.0003±0.0003 | 0.0002±0.0002 | 0.0005±0.0006 | 0.0008±0.0006 | 0.0005±0.0004 |
| MBF k 11, mL/min/100 g | 210.04±129.1 | 101.54±69.18 | 121.55±50.69 | 211.79±112.97 | 93.38±116.72 | 57.41±34.83 | 116.12±94.79 | 225.27±102.69 | 159.5±152.62 |
| MBF k 22, mL/min/100 g | 107.25±61.7 | 35.68±48.67 | 53.46±34.88 | 95.48±81.25 | 34.33±25.08 | 23.07±13.29 | 57.34±57.52 | 89.47±59.42 | 44.1±41.68 |
| MBF k 33, mL/min/100 g | 50.52±49.15 | 13.77±19.89 | 21.41±21.93 | 34.02±37.01 | 15.11±14.61 | 10.35±8.84 | 26.06±32.72 | 47.71±32.96 | 26.75±24.74 |
| DP, mm Hg | 12.09±11.06 | 31.18±19.23 | 10.35±6.06 | 6.77±4.27 | 54.05±30.46 | 50.2±34.12 | 39.43±31.56 | 16.24±9.12 | 44.99±52.12 |
| MBFk11 DP, mL/min/100 g | 130.22±80.04 | 162.36±110.61 | 64.51±26.9 | 73.53±39.22 | 258.84±323.52 | 147.79±89.68 | 234.8±191.68 | 187.61±85.53 | 368±352.12 |
| MBFk22 DP, mL/min/100 g | 66.5±38.26 | 57.05±77.82 | 28.37±18.51 | 33.15±28.21 | 95.15±69.53 | 59.39±34.21 | 115.95±116.3 | 74.51±49.49 | 101.75±96.17 |
| MBFk33 DP, mL/min/100 g | 31.32±30.47 | 22.02±31.81 | 11.36±11.64 | 11.81±12.85 | 41.87±40.48 | 26.65±22.77 | 52.69±66.17 | 39.73±27.45 | 61.72±57.07 |
Data shown as mean±SD (standard deviation) of diagonal elements of permeability tensors (k 11, k 22, and k 33); MBF according to k 11, k 22, and k 33 and constant AV DP (MBFk11, MBFk22, and MBFk33); AV DP; and MBF using the calculated varying DP in row 7 (MBFk11 DP, MBFk22 DP, and MBFk33 DP) when the scaling factor to account for oversimplification of the network is not applied. The AV path is assumed equal to 512 μm. I1MI, I3MI, I7MI, and I45MI indicate infarcted areas at 1, 3, 7. and 45 days, respectively, after MI. Similarly, R1MI, R3MI, R7MI, and R45MI indicate remote areas at 1, 3, 7, and 45 days, respectively, after MI. AV indicates arteriole–venule; DP, drop in pressure. MBF, myocardial blood flow; MI, myocardial infarction.