Table 3.
Change of the Permeability Tensor Diagonal Elements Based on Simulations of Different Vascular Remodeling Scenarios Using Tissue Under Basal Conditions
| Simulated condition | k 11 | k 22 | k 33 |
|---|---|---|---|
| Dilation of all vessels | |||
| Dilation by 10% | 99.64±117.77% | 159.24±384.3% | 73.1±43.29% |
| Dilation by 20% | 520.41±441.23% | 704.54±1300.18% | 363.46±128.96% |
| Dilation by 30% | 1819.27±1356.5% | 2304.74±3732.15% | 1264.64±419.89% |
| 30% increase of randomly selected vessels | |||
| Dilation of 10% of vessels | 43.8±71.88% | 85.61±257.62% | 33.39±32.69% |
| Dilation of 20% of vessels | 144.06±120.81% | 228.87±502.1% | 107.14±55.8% |
| Dilation of 30% of vessels | 252.33±170.04% | 366.82±671.26% | 196.15±85.2% |
| Constriction of all vessels | |||
| Constriction by 10% | −24.98±33.76% | −1.35±141.88% | −26.2±17.82% |
| Constriction by 20% | −67.34±12.77% | −50.4±85.2% | −67.1±8.78% |
| Constriction by 30% | −95.78±1.66% | −94.12±8.88% | −95.63±1.47% |
| 20% decrease in diameter of randomly selected vessels | |||
| Constriction of 10% of vessels | 15.57±62.18% | 67.9±247.79% | 12.93±26.15% |
| Constriction of 20% of vessels | 40.48±108.09% | 113.06±367.61% | 26.09±26.28% |
| Constriction of 30% of vessels | 14.35±69.97% | 81.8±292.1% | 7.93±26.1% |
| Pruning of a percentage of the smallest microvessels | |||
| Pruning of 10% of vessels | 1.4±101.63% | 144.59±348.61% | 44.22±100.56% |
| Pruning of 20% of vessels | 106.77±286.96% | 239.88±577.49% | 56.26±106.24% |
| Pruning of 30% of vessels | 517.65±990.66% | 240.04±467.5% | 48.99±161.30% |
Data shown as mean±SD of the percentage of change of the permeability tensor diagonal elements k 11, k 22, and k 33 based on simulations of different vascular remodeling scenarios using tissue under basal conditions: (1) dilation of all microvessels comprising the microvasculature by incrementing their diameter by 10%, 20%, and 30%; (2) dilation of the 10%, 20%, and 30% of microvessels by increasing their diameter by 30%; (3) constriction of all microvessels comprising the microvasculature by incrementing their diameter by 10%, 20%, and 30%; (4) constriction of the 10%, 20%, and 30% of microvessels by decreasing their diameters by 20%; and (5) pruning of the 10%, 20%, and 30% of the smallest microvessels of the microvasculature.