Table 2.
Aortic Stiffness and Endothelial Function
| Surgery (n=28) | Balloon Dilation (n=23) | Stent (n=24) | P Value | |
|---|---|---|---|---|
| CMR parameters | ||||
| PWV, m/s | ||||
| Total | 4.0±0.5 | 4.2±0.9 | 4.2±0.7 | 0.72 |
| Aortic arch | 4.7±1.5 | 4.0±1.2 | 5.5±3.8 | 0.12 |
| Mid DAO | 3.8±0.9 | 4.0±1.3 | 3.9±1.4 | 0.87 |
| Distal DAO | 4.4±1.6 | 4.8±1.7 | 4.5±1.5 | 0.70 |
| Strain | ||||
| AAO | 0.38±0.14 | 0.51±0.25 | 0.36±0.19 | 0.02 |
| Proximal DAO | 0.27±0.09 | 0.31±0.13 | 0.30±0.15 | 0.47 |
| Mid DAO | 0.37±0.11 | 0.36±0.10 | 0.36±0.16 | 0.97 |
| Distal DAO | 0.37±0.14 | 0.40±0.12 | 0.30±0.12 | 0.04 |
| Distensibility (10−3 mm Hg −1) | ||||
| AAO | 7.8±3.6 | 9.8±5.2 | 6.6±4.3 | 0.05 |
| Proximal DAO | 5.6±2.1 | 6.1±3.3 | 5.6±2.7 | 0.71 |
| Mid DAO | 7.5±2.5 | 6.9±3.3 | 6.8±3.4 | 0.67 |
| Distal DAO | 7.8±4.1 | 7.5±3.1 | 5.9±3.2 | 0.15 |
| β stiffness index | ||||
| AAO | 1.76±0.73 | 1.59±1.15 | 2.49±1.48 | 0.02 |
| Proximal DAO | 2.53±1.59 | 2.63±1.89 | 2.50±0.96 | 0.96 |
| Mid DAO | 1.75±0.76 | 1.93±0.75 | 2.15±1.11 | 0.26 |
| Distal DAO | 1.84±0.91 | 1.72±0.68 | 2.98±3.70 | 0.11 |
| Applanation tonometry | ||||
| cfPWV, m/s | 5.2±0.9 | 5.3±1.1 | 5.0±0.9 | 0.64 |
| AI at HR 75 bpm, % | −14±13 | −13±21 | −6±18 | 0.24 |
| Central SBP, mm Hg | 114±18 | 109±14 | 112±21 | 0.60 |
| Central PP, mm Hg | 50±20 | 46±13 | 45±19 | 0.49 |
| Endo‐PAT | ||||
| Endo‐PAT index | 2.15±0.77 | 2.00±0.78 | 2.25±0.68 | 0.51 |
Values are mean±SD. AAO indicates ascending aorta; AI, augmentation index; aortic arch PWV, AAO to proximal DAO pulse wave velocity; cfPWV, carotid‐femoral pulse wave velocity; DAO, descending aorta; Endo‐PAT, endothelial pulse amplitude testing; HR, heart rate; PP, pulse pressure; SBP, systolic blood pressure; total PWV, AAO to distal DAO pulse wave velocity.