Table 4.

A1M Outcome Table

Reference	Population	Dose		Blood pressure (mmHg)		Proteinuria
		A1M	Control	A1M	Control	A1M	Control
Erlandsson, 2014 [29]	STOX1 transgene mouse model (n = NR)	A1M injections from DG6	Placebo, buffer solution	Unknown. States that A1M significantly reduced hypertension throughout pregnancy.	N/A	Unknown. States that A1M significantly reduced proteinuria throughout pregnancy.	N/A
Naav, 2015 [30]	Rabbits infused with 20 mg/kg of HbF (n = 19)	6 mg/kg of A1M	Nothing	HbF didn’t increase BP		11 μg/mL of albumin*	57 μg/mL of albumin
Wester-Rosenlof, 2014 [11]	Ewes starved for 36 h (n = 11)	2 bolus doses of 1.8 mg A1M/kg body weight 2 h apart	2 separate 50 mL doses of buffer solution	MAP 36 h post treatment: 58.5*	MAP 36 h post treatment: 73.5

RED: Approximate value obtained by graph extrapolation

MAP mean arterial pressure, DG day of gestation, BP blood pressure

*statistically significant at p < 0.05