Table 5.
MSCs Outcome Table
| Reference | Population | Dose | Blood pressure (mmHg) | Proteinuria | |||
|---|---|---|---|---|---|---|---|
| MSC | Control | MSC | Control | MSC | Control | ||
| Fu, 2015 [12] | Rats treated with 2 mL endotoxin (n = 21) | MSCs suspended in 100 μL phosphate-buffered saline (2 × 106 cells/100 μL) | Nothing | Systolic DG8: 113 DG15: 124.5* DG19: 124.0* | Systolic DG8: 112 DG15: 131.0 DG19: 135.5 | DG9: 3.15 mol/L DG16: 4.60 mol/L* DG20: 5.60 mol/L* | DG9: 3.20 mol/L DG16: 3.65 mol/L DG20: 3.90 mol/L |
| Liu, 2014 [32] | Mice injected with 107 activated Th1 cells at DG10.5 and DG12.5 (n = 24) | MSCs suspended in 100 mL of PBS (106 cells/100 mL) injected on DG 11.5 and DG 13.5 | Nothing | Systolic DG14: 135** | Systolic DG14: 182 | DG14: 750 mg/L | DG14: 750 mg/L |
| Wang, 2016 [33] | Pregnant rats treated with 1 μg/kg LPS solution (n = 21) | 2 × 106 MSCs per rat | Nothing | Systolic DG12: 116.27 ± 0.61 DG15: 125.08 + 3.42 DG18: 124.29 ± 3.71* | Systolic DG12: 115.65 ± 1.15 DG15: 127.41 ± 3.25 DG18: 139.50 ± 2.38 | DG13: 3.10 ± 0.71 mol/Ln DG16: 3.81 ± 0.70 mol/L DG19: 4.54 ± 0.64 mol/L* | DG13: 3.06 ± 0.50 mg DG16: 4.55 ± 0.57mgn DG19: 5.56 ± 1.22 mg |
RED: Approximate value obtained by graph extrapolation
DG day of gestation, LPS Lipopolysaccharide, PBS phosphate buffered saline
*Statistically significant at p < 0.05
**Statistically significant at p < 0.01