Fig. 12.

Loss of BBS8 protein is associated with increased expression of molecular inducers of neuro-inflammation in brains of BBS8^-\- mice. Expression of molecular inducers of neuro-inflammation in brains of control mice, Cre+, and Bbs8^−/− mice are summarized and graph showing relative mRNA expression of molecular inducers of neuro-inflammation in brains of corresponding control mice, Bbs8^flox; Cre + mice, and Bbs8^−/− mice. Data are presented as Mean + SEM, a) wt and BBS8^-\- mice (n = 4/genotype), b) Bbs8^flox; Cre- and Bbs8^flox; Cre + mice (n = 4/genotype, P value style APA: 0.12 non-significant, 0.033 (*), 0.002(**) and p < .001(***))