Table 5.
The most significant chromosome bands only enriched in our method
| Chromosome band | P value | Module ID | CNVs validated in separate cohorts(TCGA, METABRIC) |
|---|---|---|---|
| GSE31684 | |||
| 4q13.3 | 2.47e-06 | 13 | Yes,NA |
| Yp11.2 | 8.25e-04 | 12 | No,NA |
| Yq11.223 | 8.25e-04 | 12 | No,NA |
| 4q21.1 | 8.35e-04 | 4 | Yes,NA |
| 19p13.12 | 1.25e-03 | 5 | No,NA |
| GSE54002 | |||
| 11p15.1 | 1.92e-12 | 44 | Yes,Yes |
| 11q12.2 | 1.61e-06 | 19 | Yes,Yes |
| 19q13.31 | 1.03e-05 | 61 | Yes,Yes |
| 9q31.3 | 2.12e-05 | 26 | No,Yes |
| 9q22.33 | 2.28e-05 | 26 | No,Yes |
| GSE102484 | |||
| 8p11.23 | 3.97e-19 | 53 | Yes,Yes |
| 9q34.3 | 1.36e-09 | 14 | Yes,Yes |
| 15q22.31 | 4.21e-09 | 27 | Yes,Yes |
| 13q14.3 | 2.27e-08 | 18 | Yes,Yes |
| 7q36.3 | 4.12e-08 | 7 | Yes,Yes |
P value cutoff = 0.01