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. 2019 May 3;13:188. doi: 10.3389/fncel.2019.00188

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Copyright © 2019 Sanguinetti, Guzzardi, Panetta, Tripodi, De Sena, Quaglierini, Burchielli, Salvadori and Iozzo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cognitive function parameters at the age of 8 (A) and 14 months (B). Data are presented as mean ± SEM. Sample sizes are given in Table 1. P_trend refers to regression analyses across the first four groups. *p < 0.05 or less (**,***) ND-ND and HFD-HFD (between strains), $^{\land}$ p < 0.05 or less ( $^{\land}$ $^{\land}$ ) HFD vs. ND (within-strain), ^$#$p < 0.05 or less (^{$# #$},^{$# # #$}) vs. ND control group (reference group), °p < 0.05 or less (°°,°°°) for treated 3×Tg-HFD + INI vs. untreated 3×Tg-HFD.