TABLE 2.
Two-way ANOVA for the effects of diet and genotype in group comparisons.
| Diet | Genotype | Diet* Genotype | |
|---|---|---|---|
| 8 months | |||
| Body weight (g) | <0.0005 | <0.0005 | 0.793 |
| Body mass index (kg/m2) | <0.0005 | 0.108 | 0.990 |
| AUC body weight (g*time) | 0.015 | <0.0005 | 0.961 |
| Random glycemia (mmol/l)(21-22w) | 0.001 | <0.0005 | 0.035 |
| Insulin (pg/ml) | 0.952 | 0.806 | 0.153 |
| Leptin (pg/ml) | 0.039 | <0.0005 | 0.036 |
| Resistin (pg/ml) | 0.045 | 0.906 | 0.297 |
| IL-6 (pg/ml) | 0.937 | 0.187 | 0.724 |
| TNF-alpha (pg/ml) | 0.343 | 0.791 | 0.672 |
| MCP-1 (pg/ml) | 0.580 | 0.004 | 0.561 |
| PAI-1 (pg/ml) | 0.204 | 0.001 | 0.555 |
| Alternation triplets (n) | 0.125 | <0.005 | 0.659 |
| Alternation triplets (%) | 0.143 | <0.005 | 0.401 |
| Resting time (s) | 0.416 | 0.248 | 0.437 |
| Total arm entries (n) | 0.444 | 0.353 | 0.052 |
| Total distance (cm) | 0.133 | 0.106 | 0.259 |
| Speed (cm/s) | 0.141 | 0.106 | 0.252 |
| Latency time (s) | 0.825 | 0.293 | 0.946 |
| Zone transition (n) | 0.340 | 0.252 | 0.080 |
| Brain mass (g) | 0.333 | 0.239 | 0.710 |
| Cerebral SUV (% ID/g) baseline | 0.528 | <0.005 | 0.849 |
| Cerebral SUV (% ID/g) + insulin | 0.434 | <0.005 | 0.756 |
| Cerebral GU (% ID/g * mmol/l) baseline | <0.005 | 0.067 | 0.351 |
| Cerebral GU (% ID/g * mmol/l) + insulin | <0.005 | 0.593 | 0.477 |
| 14 months | |||
| Body weight (g) | 0.004 | 0.001 | 0.214 |
| Body mass index (kg/m2) | 0.011 | 0.658 | 0.167 |
| AUC body weight (g*time) | 0.011 | <0.0005 | 0.230 |
| Random glycemia (mmol/l) | 0.003 | <0.0005 | 0.796 |
| Insulin (pg/ml) | 0.182 | 0.004 | 0.092 |
| Leptin (pg/ml) | 0.026 | <0.0005 | 0.178 |
| Resistin (pg/ml) | 0.022 | 0.025 | 0.131 |
| IL-6 (pg/ml) | 0.543 | <0.0005 | 0.063 |
| TNF-alpha (pg/ml) | 0.060 | 0.384 | 0.162 |
| MCP-1 (pg/ml) | 0.669 | 0.005 | 0.576 |
| PAI-1 (pg/ml) | 0.589 | 0.029 | 0.460 |
| Alternation triplet (n) | 0.120 | <0.0005 | 0.495 |
| Alternation triplet (%) | 0.727 | 0.001 | 0.796 |
| Resting time (s) | 0.127 | <0.005 | 0.154 |
| Total arm entries (n) | 0.004 | 0.085 | 0.079 |
| Total distance (cm) | 0.091 | <0.0005 | 0.222 |
| Speed (cm/s) | 0.100 | <0.0005 | 0.241 |
| Latency time (s) | 0.188 | 0.054 | 0.300 |
| Zone transition (n) | 0.004 | 0.077 | 0.083 |
| Brain mass (g) | 0.732 | <0.005 | 0.270 |
| Cerebral SUV (% ID/g) baseline | 0.346 | 0.001 | 0.871 |
| Cerebral SUV (% ID/g) + insulin | 0.824 | 0.001 | 0.318 |
| Cerebral GU (% ID/g * mmol/l) baseline | 0.511 | 0.136 | 0.827 |
| Cerebral GU (% ID/g * mmol/l) + insulin | 0.268 | 0.607 | 0.644 |
In bold are indicated significant p-values.