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. 2019 May 3;10:416. doi: 10.3389/fgene.2019.00416

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Copyright © 2019 Xuan, Cao, Zhang, Kong and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of the feature matrix of lncRNA l₁ and disease d₂. (A) Construct the first part of feature matrix by integrating the lncRNA similarities and the lncRNA-disease associations. (B) Construct the second part by incorporating the lncRNA-disease associations and the disease similarities. (C) Construct the third part by exploiting the lncRNA-miRNA interactions and the miRNA-disease associations. (D) Concatenate these three parts to form the feature matrix P.